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Crest Gum Detoxify is a brand-new line of toothpastes that is clinically proven to neutralize the harmful bacteria around your gum line. When you brush, it produces a cooling foam that cleans deeply, penetrating hard-to-reach areas your toothbrush can’t always get. Gum Detoxify uses an active ingredient known as stannous fluoride (or SNF2) which binds to the toxic bacteria, not only killing it, but neutralizing its effect on your gums.